Fragmentation of protonated O,O-diethyl O-aryl phosphorothionates in tandem mass spectral analysis
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چکیده
منابع مشابه
Fragmentation pathways of protonated peptides.
The fragmentation pathways of protonated peptides are reviewed in the present paper paying special attention to classification of the known fragmentation channels into a simple hierarchy defined according to the chemistry involved. It is shown that the 'mobile proton' model of peptide fragmentation can be used to understand the MS/MS spectra of protonated peptides only in a qualitative manner r...
متن کاملExperimental protein mixture for validating tandem mass spectral analysis.
Several methods have been used to identify peptides that correspond to tandem mass spectra. In this work, we describe a data set of low energy tandem mass spectra generated from a control mixture of known protein components that can be used to evaluate the accuracy of these methods. As an example, these spectra were searched by the SEQUEST application against a human peptide sequence database. ...
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00 Diethyl 0 -p -nitrophenyl thiophosphate (I), generally known as parathion or E 605, is an insecticide which is of value against a variety of crop pests. Its mammalian toxicity is usually ascribed to its power of inhibiting cholinesterase, and this is also possibly its mechanism of insecticidal action. The in vitro inhibition of the enzyme was first studied by DuBois, Doull, Salerno & Coon (1...
متن کاملA cholinesterase inhibitor derived from OO-diethyl O-p-nitrophenyl thiophosphate in vivo.
in the urine, and the kidney must have a considerable power of concentrating formate. The inhibition of the appearance of formate during the administration ofethanol is in accordance with Zatman's (1946) interpretation of the earlier experiments, namely, that a primary oxidation of methanol to formaldehyde through the agency of alcohol dehydrogenase is competitively inhibited by ethanol. More r...
متن کاملFragmentation cross sections of protonated water clusters.
We have measured fragmentation cross sections of protonated water cluster cations (H(2)O)(n=30-50)H(+) by collision with water molecules. The clusters have well-defined sizes and internal energies. The collision energy has been varied from 0.5 to 300 eV. We also performed the same measurements on deuterated water clusters (D(2)O)(n=5-45)D(+) colliding with deuterated water molecules. The main f...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 1996
ISSN: 1044-0305,1879-1123
DOI: 10.1016/1044-0305(95)00634-6